| Date | Location | Result | |
| 5/14/2022 | Schenectady, N.Y. | Union (N.Y.) 14, John Carroll 7 | Box score |
| 5/11/2022 | University Hts., OH | John Carroll 11, North Central 3 | Box score |
| 5/7/2022 | Berea, Ohio | John Carroll 10, Baldwin Wallace 4 | Box score |
| 5/4/2022 | University Hts., OH | John Carroll 15, Ohio Northern 4 | Box score |
| 4/27/2022 | University Hts., OH | John Carroll 19, Mount Union 5 | Box score |
| 4/23/2022 | New Concord, Ohio | John Carroll 18, Muskingum 5 | Box score |
| 4/20/2022 | University Hts., OH | Baldwin Wallace 9, John Carroll 8 | Box score |
| 4/15/2022 | University Hts., OH | John Carroll 14, Ohio Northern 6 | Box score |
| 4/9/2022 | Wilmington, Ohio | John Carroll 29, Wilmington (OH) 0 | Box score |
| 4/6/2022 | Tiffin | John Carroll 29, Heidelberg 1 | Box score |
| 4/2/2022 | University, Hts., OH | John Carroll 21, Capital 6 | Box score |
| 3/30/2022 | Westerville, Ohio | John Carroll 18, Otterbein 5 | Box score |
| 3/26/2022 | Marietta, Ohio | John Carroll 13, Marietta College 7 | Box score |
| 3/23/2022 | Granville, Ohio | Denison 11, John Carroll 5 | Box score |
| 3/19/2022 | University Hts., OH | John Carroll 16, SUNY Brockport 15 | Box score |
| 3/12/2022 | University, Hts., OH | John Carroll 12, Ohio Wesleyan 11 | Box score |
| 3/9/2022 | Grove City, Pa. | John Carroll 12, Grove City 10 | Box score |
| 3/5/2022 | University Hts., OH | John Carroll 15, Aurora 4 | Box score |
| 3/2/2022 | Springfield, OH | John Carroll 21, Wittenberg 16 | Box score |
| 2/23/2022 | University Hts, OH | John Carroll 21, Wooster 4 | Box score |