| Date | Location | Result | |
| 03/05/22 | Angola, IN | Trine 63, John Carroll 42 | Box score |
| 03/04/22 | Angola, IN | John Carroll 100, Elizabethtown 56 | Box score |
| 02/26/22 | University Heights, OH | Baldwin Wallace 60, John Carroll 50 | Box score |
| 02/24/22 | University Heights, OH | John Carroll 64, Ohio Northern 50 | Box score |
| 02/22/22 | University Heights, OH | John Carroll 79, Wilmington (OH) 64 | Box score |
| 02/19/22 | University Heights, OH | John Carroll 85, Wilmington (OH) 59 | Box score |
| 02/16/22 | Berea, OH | John Carroll 67, Baldwin Wallace 54 | Box score |
| 02/12/22 | University Heights, OH | John Carroll 68, Ohio Northern 43 | Box score |
| 02/09/22 | University Heights, OH | Otterbein 57, John Carroll 52 | Box score |
| 02/05/22 | Marietta, OH | John Carroll 83, Marietta 67 | Box score |
| 02/01/22 | Tiffin, OH | John Carroll 105, Heidelberg 71 | Box score |
| 01/29/22 | Bexley, OH | John Carroll 74, Capital 41 | Box score |
| 01/26/22 | University Heights, OH | John Carroll 77, Mount Union 50 | Box score |
| 01/22/22 | University Heights, OH | John Carroll 93, Muskingum 42 | Box score |
| 01/19/22 | University Heights, OH | John Carroll 68, Baldwin Wallace 65 | Box score |
| 01/15/22 | Wilmington, OH | John Carroll 76, Wilmington (OH) 56 | Box score |
| 01/12/22 | Westerville, OH | John Carroll 52, Otterbein 47 | Box score |
| 01/08/22 | Ada, OH | John Carroll 54, Ohio Northern 49 | Box score |
| 12/21/21 | Lexington, KY | John Carroll 67, Maryville (TN) 64 | Box score |
| 12/20/21 | Lexington, KY | Transylvania 83, John Carroll 75 | Box score |
| 12/18/21 | University Heights, OH | Marietta 81, John Carroll 80 | Box score |
| 12/11/21 | University Heights, OH | John Carroll 73, Capital 55 | Box score |
| 12/08/21 | Alliance, OH | John Carroll 69, Mount Union 56 | Box score |
| 12/04/21 | New Concord, OH | John Carroll 76, Muskingum 68 | Box score |
| 11/23/21 | University Heights, OH | John Carroll 93, Denison 47 | Box score |
| 11/20/21 | University Heights, OH | John Carroll 75, Albion 66 | Box score |
| 11/13/21 | University Heights, OH | John Carroll 79, Carnegie Mellon 62 | Box score |
| 11/12/21 | University Heights, OH | John Carroll 77, CWRU 65 | Box score |