| Date | Location | Result | |
| 11/02/2021 | New Concord, OH | Muskingum 3, John Carroll 0 (25-20,25-23,25-23) | |
| 10/30/2021 | Wilmington, OH | John Carroll 3, Olivet 1 (25-9,23-25,25-18,25-18) | |
| 10/30/2021 | Wilmington, OH | John Carroll 3, Wilmington (OH) 0 (25-14,25-18,25-22) | |
| 10/27/2021 | University Hts., OH | Heidelberg 3, John Carroll 2 (25-21,19-25,25-23,22-25,15-10) | |
| 10/23/2021 | University Hts., OH | John Carroll 3, Marietta 0 (25-18,25-18,25-15) | |
| 10/20/2021 | Berea, OH | John Carroll 3, Baldwin Wallace 2 (12-25,26-24,25-21,24-26,15-13) | |
| 10/16/2021 | Ada, OH | Ohio Northern 3, John Carroll 0 (25-23,25-14,25-14) | |
| 10/13/2021 | University Hts., OH | Otterbein 3, John Carroll 0 (25-14,24-21,25-22) | |
| 10/9/2021 | University Hts., OH | John Carroll 3, Capital 0 (25-13,25-17,25-20) | |
| 10/6/2021 | Alliance, OH | Mount Union 3, John Carroll 1 (20-25,25-20,25-22,25-23) | |
| 10/2/2021 | Elmhurst, Ill. | John Carroll 3, Alma 0 (25-20,25-16,25-16) | |
| 10/1/2021 | Elmhurst, IL | John Carroll 3, Augustana (IL) 1 (21-25,25-21,25-19,25-18) | |
| 10/1/2021 | Elmhurst, IL | Coe 3, John Carroll 0 (25-22,25-20,25-19) | |
| 9/29/2021 | University Hts, OH | CWRU 3, John Carroll 0 (25-19,26-24,25-20) | |
| 9/25/2021 | Granville, OH | Earlham 3, John Carroll 0 (25-21,25-19,25-22) | |
| 9/25/2021 | Granville, OH | Denison 3, John Carroll 1 (25-21,18-25,25-20,25-20) | |
| 9/22/2021 | New Concord, OH | Muskingum 3, John Carroll 0 (25-16,25-20,25-23) | |
| 9/18/2021 | Oberlin, OH | John Carroll 3, North Park 0 (26-24,25-19,25-22) | |
| 9/18/2021 | Oberlin, OH | Oberlin 3, John Carroll 0 (27-25,25-18,25-19) | |
| 9/17/2021 | University Hts., OH | Geneva 3, John Carroll 1 (25-22,27-25,12-25,25-21) | |
| 9/15/2021 | University Hts., OH | Ohio Wesleyan 3, John Carroll 1 (23-25,25-11,25-20,25-21) | |
| 9/11/2021 | Erie, PA | John Carroll 3, Fredonia 0 (25-22,25-17,25-20) | |
| 9/11/2021 | Erie, Penn. | John Carroll 3, Bluffton University 1 (25-18,23-25,25-19,25-19) | |
| 9/10/2021 | PSU Behrend | John Carroll 3, Westminster (PA) 1 (16-25,25-19,25-19,25-16) | |
| 9/10/2021 | Erie, PA | John Carroll 3, Penn St.-Behrend 2 (22-25,25-22,25-21,16-25,15-6) | |
| 9/8/2021 | Hiram, OH | Hiram 3, John Carroll 0 (25-18,25-17,25-21) | |
| 9/4/2021 | Cleveland, OH | Albion 3, JOHN CARROLL 0 (25-22,25-20,25-22) | |
| 9/3/2021 | Cleveland, OH | Earlham 3, JOHN CARROLL 1 (25-13,25-27,26-24,25-22) | |
| 9/3/2021 | Cleveland, OH | JOHN CARROLL 3, Bethany 2 (24-26,20-25,25-22,25-19,15-12) | |
| 9/1/2021 | Wooster, OH | JOHN CARROLL 3, College of Wooster 1 (25-21,25-22,19-25,25-15) |