| Date | Location | Result | |
| 02/22/22 | Alliance, OH | Mount Union 93, John Carroll 65 | Box score |
| 02/21/22 | Wilmington, OH | John Carroll 78, Wilmington (OH) 72 | Box score |
| 02/19/22 | University Heights, OH | Wilmington (OH) 85, John Carroll 84 | Box score |
| 02/16/22 | University Heights, OH | Baldwin Wallace 88, John Carroll 77 | Box score |
| 02/12/22 | University Heights, OH | Ohio Northern 74, John Carroll 71 | Box score |
| 02/09/22 | Westerville, OH | Otterbein 79, John Carroll 73 | Box score |
| 02/05/22 | Marietta, OH | Marietta 88, John Carroll 74 | Box score |
| 02/01/22 | University Heights, OH | Heidelberg 76, John Carroll 74 | Box score |
| 01/28/22 | Bexley, OH | Capital 97, John Carroll 79 | Box score |
| 01/26/22 | Alliance, OH | Mount Union 89, John Carroll 80 | Box score |
| 01/22/22 | University Heights, OH | John Carroll 91, Muskingum 83 | Box score |
| 01/19/22 | Berea, OH | Baldwin Wallace 101, John Carroll 64 | Box score |
| 1/15/22 | Wilmington, OH | Wilmington (OH) 94, John Carroll 73 | Box score |
| 01/12/22 | University Heights, OH | Otterbein 81, John Carroll 75 | Box score |
| 12/30/21 | Huntingdon, PA | John Carroll 99, Bryn Athyn 76 | Box score |
| 12/29/21 | Huntingdon, PA | Rowan 110, John Carroll 91 | Box score |
| 12/10/21 | University Heights, OH | Capital 85, John Carroll 67 | Box score |
| 12/08/21 | University Heights, OH | Mount Union 93, John Carroll 83 | Box score |
| 12/04/21 | Zanesville, OH | John Carroll 87, Muskingum 84 | Box score |
| 11/27/21 | Cleveland, OH | Case Western Reserve 111, John Carroll 82 | Box score |
| 11/20/21 | Buffalo, NY | John Carroll 93, Buffalo St. 84 | Box score |
| 11/19/21 | Buffalo, NY | John Carroll 92, Medaille 76 | Box score |
| 11/13/21 | Hamburg, NY - Hafner Recreation Center | John Carroll 100, Hilbert 79 | Box score |
| 11/12/21 | Hamburg, NY - Hafner Recreation Center | John Carroll 109, Keuka 96 | Box score |